2021 Orlando City (1-0-2)

17 Apr T Atlanta 0- 0  
(0-0-1)
23 Apr T at Sporting KC 1- 1  
(0-0-2)
1 May W Cincinnati 3- 0  
(1-0-2)
8 May NY City FC  
 
16 May at DC United  
 
22 May Toronto  
 
29 May at NY Red Bulls  
 
19 Jun at Toronto  
 
22 Jun San Jose  
 
25 Jun at Miami  
 
3 Jul NY Red Bulls  
 
7 Jul at Chicago  
 
17 Jul at Toronto  
 
22 Jul Philadelphia  
 
25 Jul at NY City FC  
 
30 Jul Atlanta  
 
4 Aug Miami  
 
7 Aug at Cincinnati  
 
18 Aug at Nashville  
 
21 Aug Chicago  
 
27 Aug Miami  
 
4 Sep Columbus  
 
10 Sep at Atlanta  
 
15 Sep Montreal  
 
19 Sep at Philadelphia  
 
25 Sep at New England  
 
29 Sep at Nashville  
 
2 Oct DC United  
 
16 Oct at Cincinnati  
 
20 Oct Montreal  
 
24 Oct New England  
 
27 Oct at Columbus  
 
31 Oct Nashville  
 
7 Nov at Montreal