2021 Houston Dynamo (1-1-1)

16 Apr W San Jose 2- 1  
(1-0-0)
24 Apr L at Portland 1- 2  
(1-1-0)
1 May T Los Angeles FC 1- 1  
(1-1-1)
8 May at FC Dallas  
 
12 May Sporting KC  
 
15 May at Colorado  
 
22 May Vancouver  
 
29 May at Sporting KC  
 
19 Jun at Los Angeles FC  
 
23 Jun Portland  
 
26 Jun at Real Salt Lake  
 
3 Jul Cincinnati  
 
7 Jul at Seattle  
 
21 Jul at Vancouver  
 
24 Jul at San Jose  
 
31 Jul Real Salt Lake  
 
4 Aug at Real Salt Lake  
 
7 Aug at Minnesota  
 
14 Aug Colorado  
 
18 Aug at Real Salt Lake  
 
21 Aug FC Dallas  
 
28 Aug Minnesota  
 
3 Sep Portland  
 
11 Sep Portland  
 
15 Sep at LA Galaxy  
 
18 Sep FC Dallas  
 
25 Sep at Minnesota  
 
29 Sep Vancouver  
 
3 Oct at Sporting KC  
 
16 Oct Seattle  
 
20 Oct LA Galaxy  
 
24 Oct at LA Galaxy  
 
31 Oct Colorado  
 
3 Nov at Montreal