1916 Mississippi College (4-3) Independent

Wk 4 Fri 6 Oct W vs Mississippi St 13- 6   (1-0)
Wk 5 Sat 14 Oct L at Alabama 7- 13   (1-1)
Wk 6 Sat 21 Oct L at LSU 7- 50   (1-2)
Wk 7 Fri 27 Oct L vs Tulane 3- 13   (1-3)
Wk 9 Tue 7 Nov W at Southern Miss 75- 0   (2-3)
Wk 10 Sat 18 Nov W Ouachita 26- 0   (3-3)
Wk 12 Thu 30 Nov W vs Ole Miss 36- 14   (4-3)