1910 Villanova (0-4-2) Independent

Wk 2 Sat 24 Sep L vs Carlisle 0- 6   (0-1)
Wk 3 Sat 1 Oct L at Princeton 0- 36   (0-2)
Wk 5 Sat 15 Oct T at North Carolina St 6- 6 (0-2-1)
Wk 7 Sat 29 Oct T at Penn St 0- 0 (0-2-2)
Wk 9 Sat 12 Nov L at Army 0- 13   (0-3-2)
Wk 10 Sat 19 Nov L at Washington & Jefferson 0- 9   (0-4-2)