2021-22 Winthrop (23-9) Big South

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9 Nov W Mary Baldwin 110- 78
(1-0)
13 Nov W Mercer 88- 85 (O)
(2-0)
16 Nov L at Middle Tenn St 65- 76
(2-1)
20 Nov L at Vanderbilt 63- 77
(2-2)
22 Nov L at Washington St 86- 92
(2-3)
27 Nov W at Washington 82- 74
(3-3)
1 Dec W Hartford 82- 75
(4-3)
4 Dec L at Coastal Carolina 64- 74
(4-4)
7 Dec W Furman 85- 80
(5-4)
11 Dec W vs Carver 83- 52
(6-4)
15 Dec L at Elon 61- 63
(6-5)
21 Dec L vs Mississippi St 63- 84
(6-6)
31 Dec W Converse 78- 40
(7-6)
10 Jan W Campbell 74- 72
(8-6)
13 Jan W NC-Asheville 86- 80 (O)
(9-6)
15 Jan W at Charleston Southern 70- 65
(10-6)
20 Jan W at Presbyterian 60- 58
(11-6)
22 Jan W Gardner-Webb 64- 62
(12-6)
24 Jan L at High Point 56- 65
(12-7)
26 Jan W at SC-Upstate 95- 91 (O)
(13-7)
29 Jan L at Longwood 88- 92
(13-8)
3 Feb W North Carolina A&T 64- 54
(14-8)
5 Feb W at Hampton 69- 57
(15-8)
9 Feb W Radford 58- 48
(16-8)
12 Feb W Presbyterian 65- 61
(17-8)
16 Feb W at Gardner-Webb 81- 70
(18-8)
19 Feb W at NC-Asheville 84- 79
(19-8)
24 Feb W SC-Upstate 89- 59
(20-8)
26 Feb W Charleston Southern 92- 86
(21-8)
4 Mar W vs High Point 68- 51
(22-8)
5 Mar W vs Gardner-Webb 76- 67
(23-8)
6 Mar L vs Longwood 58- 79
(23-9)