1921 Newberry (3-3-1) Independent

Wk 3 Sat 1 Oct L at Furman 0- 63   (0-1)
Wk 4 Sat 8 Oct L at South Carolina 0- 7   (0-2)
Wk 5 Sat 15 Oct W Charleston 41- 0   (1-2)
Wk 7 Sat 29 Oct W at Wofford 33- 21   (2-2)
Wk 8 Sat 5 Nov T Citadel 7- 7 (2-2-1)
Wk 9 Sat 12 Nov L at Erskine 13- 18   (2-3-1)
Wk 10 Sat 19 Nov W Presbyterian 16- 7   (3-3-1)